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News in Physiological Sciences, Vol 8, 170-174, Copyright © 1993 by International Union of Physiological Sciences
ARTICLES |
MJ Koury and MC Bondurant
Hematopoietic growth factors have been thought to control blood cell production by stimulating proliferation and differentiation of hematopoietic progenitor cells. However, recent studies show that these growth factors prevent programmed death in progenitor cells. A model of hematopoiesis based on prevention of this death by hematopoietic growth factors is presented.
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