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News Physiol Sci 8: 170-174, 1993;
1548-9213/93 $5.00
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News in Physiological Sciences, Vol 8, 170-174, Copyright © 1993 by International Union of Physiological Sciences


ARTICLES

Prevention of Programmed Death in Hematopoietic Progenitor Cells by Hematopoietic Growth Factors

MJ Koury and MC Bondurant

Hematopoietic growth factors have been thought to control blood cell production by stimulating proliferation and differentiation of hematopoietic progenitor cells. However, recent studies show that these growth factors prevent programmed death in progenitor cells. A model of hematopoiesis based on prevention of this death by hematopoietic growth factors is presented.





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