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News Physiol Sci 8: 191-195, 1993;
1548-9213/93 $5.00
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News in Physiological Sciences, Vol 8, 191-195, Copyright © 1993 by International Union of Physiological Sciences


ARTICLES

Oxygen Sensing and the Electrophysiology of Arterial Chemoreceptor Cells

J Lopez-Barneo, AR Benot and J Urena

The carotid bodies sense reductions in arterial oxygen tension (PO2) and stimulate the respiratory center to induce hyperventilation. Lowering PO2, detected by O2-sensitive K+ channels, evokes a selective inhibition of the K+ current of glomus cells, with an increase of cellular excitability and cytosolic Ca2+.





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