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News Physiol Sci 8: 223-228, 1993;
1548-9213/93 $5.00
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News in Physiological Sciences, Vol 8, 223-228, Copyright © 1993 by International Union of Physiological Sciences

ARTICLES

Atrial Natriuretic Factor in Central Cardiovascular Control

S Oparil and JM Wyss

A complete atrial natriuretic factor (ANF) synthetic, processing, and effector system is found in rat brain. ANF in critical brain regions, including anterior hypothalamic area and nucleus tractus solitarii, contributes importantly to the tonic control of blood pressure, sympathetic outflow, and baroreceptor reflex sensitivity in the spontaneously hypertensive rat.


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