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News Physiol Sci 9: 20-22, 1994;
1548-9213/94 $5.00
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News in Physiological Sciences, Vol 9, 20-22, Copyright © 1994 by International Union of Physiological Sciences

ARTICLES

Actions of Insulin and the IGFs on Bone

J Verhaeghe and R Bouillon

Insulin and insulin-like growth factors (IGF) I and II have receptors in osteoblastic cells and stimulate both their proliferation and activity in vitro. Insulin probably has no effect on osteoblast precursors. Osteoclast formation is induced by IGF-I in vitro, and IGF-I may affect bone (re)modeling in vivo.


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 EndocrinologyHome page
S. Qutob, S. J. Dixon, and J. X. Wilson
Insulin Stimulates Vitamin C Recycling and Ascorbate Accumulation in Osteoblastic Cells
Endocrinology, January 1, 1998; 139(1): 51 - 56.
[Abstract] [Full Text] [PDF]


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