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News Physiol Sci 9: 64, 1994;
1548-9213/94 $5.00
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News in Physiological Sciences, Vol 9, 64-64, Copyright © 1994 by International Union of Physiological Sciences

ARTICLES

Nitric oxide Synthase: From Molecular Biology to Cerebrovascular Physiology

ZS Katusic and F Cosentino

Three distinct nitric oxide synthase genes are expressed in the cerebral arterial wall. Constitutive isoforms are localized in endothelium and perivascular nerves, whereas only inducible enzyme is present in smooth muscle cells, demonstrating the complex role of nitric oxide in regulation of cerebral arterial tone.




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