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News Physiol Sci 9: 80-84, 1994;
1548-9213/94 $5.00
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News in Physiological Sciences, Vol 9, 80-84, Copyright © 1994 by International Union of Physiological Sciences

ARTICLES

Macrophages in the Brain: Friends or Enemies?

D Piani, DB Constam, K Frei and A Fontana

Cells of the macrophage lineage are ubiquitously distributed in the body, including the central nervous system. They represent an essential host defense system to protect from infections. However, recent evidence indicates that brain macrophages may also be responsible for tissue destruction, including loss of neurons and demyelination.




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