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News Physiol Sci 9: 101-105, 1994;
1548-9213/94 $5.00
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News in Physiological Sciences, Vol 9, 101-105, Copyright © 1994 by International Union of Physiological Sciences

ARTICLES

P-Type Calcium Channels and Transmitter Release From Nerve Terminals

OD Uchitel and DA Protti

Different types of Ca2+ channels have been identified in neuronal soma. P-type Ca2+ channels resistant to the blocking effect of dihydropyridines and w-conotoxin-GVIA but sensitive to the funnel web spider toxin and w-agatoxin-IVA mediate the influx of Ca2+ involved in transmitter release in mammalian synapses.




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