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News Physiol Sci 9: 123-128, 1994;
1548-9213/94 $5.00
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News in Physiological Sciences, Vol 9, 123-128, Copyright © 1994 by International Union of Physiological Sciences

ARTICLES

Hormones and Fibrosis: A Case for Lost Reciprocal Regulation

KT Weber

Fibrogenesis represents either a necessary or an unwanted process. Stimulators of fibrosis (e.g., angiotensin II, aldosterone, and endothelins) are normally counterbalanced by inhibitors (e. g., bradykinin, prostaglandins, and glucocorticoids). Fibrosis appears when this cooperative and balanced reciprocal regulation is lost.




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