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News Physiol Sci 9: 268-271, 1994;
1548-9213/94 $5.00
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News in Physiological Sciences, Vol 9, 268-271, Copyright © 1994 by International Union of Physiological Sciences

ARTICLES

Nitric Oxide inhibition in Hypertension

V Lahera and AA Khraibi

In normotensive rats, natriuresis and diuresis resulting from a pressor dose of nitric oxide (NO) inhibitors are primarily due to a pressure-natriuresis phenomenon. In the Okamoto spontaneously hypertensive rat, administration of the same dose of NO inhibitor does not increase blood pressure but produces exaggerated natriuresis and diuresis.




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