β-Arrestins: Multifunctional Cellular Mediators

Liza Barki-Harrington, Howard A. Rockman

Abstract

Initially thought to play a role only in G-protein-coupled receptor desensitization, β-arrestins are ascribed with new roles such as scaffolding and signaling proteins by their own right. This review explores the many functions of β-arrestins, with an emphasis on their recently identified role as regulators of receptor signaling.

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