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Cover:  Toadfish swim bladder muscles and rattlesnake shaker muscles are used to produce high-frequency sounds. Necessary modifications of the contractile machinery make them the fastest vertebrate muscles known. Artwork by Robert Golder and Tamara Clarke. See "The Quest for Speed: Muscles Built for High-Frequency Contractions" by Lawrence C. Rome and Stan L. Lindstedt, p. 261, this issue.