About the Cover
On the cover: Schematic drawing of the secretory and
endocytic pathways illustrating the heterogeneous localization
of phosphoinositides on membrane of these pathways.
Phosphoinositides contribute to define an identity code for
each membrane and help recruit and regulate cytosolic
proteins at the membrane interface. Membranes enriched
in a specific phosphoinositide are color coded.
Phosphoinositides, either directly or indirectly, are implicated
in the regulation of a wide variety of cellular functions,
and a growing number of human genetic diseases is being
linked to disruption of the turnover and localization of
these phospholipids. See McCrea and De Camilli, p. 8.
[Table of Contents]
Copyright © 2009 by the Int. Union Physiol. Sci./Am. Physiol. Soc.
